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The northern end of Ruta 40

Where Argentina's longest road begins, on the Bolivian border at 3,442 m — La Quiaca, the Puna crossing to Susques and the descent to the Quebrada de Humahuaca.

By Visit NOA Editors ·

The layered rock walls of the Quebrada de Humahuaca under a wide Jujuy sky

Photo: Bachelot Pierre J-P, CC BY-SA 3.0

Experiences

Tours for this trip

  • From Jujuy: Full-Day Tour to Salinas Grandes and Purmamarca
    Free cancellation
    Viator

    Nature

    From Jujuy: Full-Day Tour to Salinas Grandes and Purmamarca

    This full-day excursion from Jujuy will discover the most interesting places. Marvel at the Cerro de los Siete Colores, pose for photos in the striking white salt flats of Salinas Grandes and shop for souvenirs at the…

    8–9 h · Purmamarca, Salinas Grandes

    From US$44

    4.2 out of 5 (19)

  • Quebrada de Humahuaca From Salta with Purmamarca
    Free cancellation
    Viator

    Culture

    Quebrada de Humahuaca From Salta with Purmamarca

    Discover the beautiful landscapes offered by the Quebrada de Humahuaca, with its picturesque villages, culture and ancestral history. The various colors, mountains and hills. The native fauna, the warmth of its people,…

    Full day · 12 h · Salta, Humahuaca, Purmamarca

    From US$56

    4.9 out of 5 (130)

  • Adventure in the Great Salt Flats in the White Desert
    Free cancellation
    Viator

    Adventure · Culture

    Adventure in the Great Salt Flats in the White Desert

    Salinas Grandes & Purmamarca: A journey to the heart of the white desert Explore the surreal beauty of the Salinas Grandes, the vast salt desert in Jujuy, on this full-day tour. Accompanied by an expert local guide,…

    Full day · 12 h · Salta, Salinas Grandes

    From US$55

    5.0 out of 5 (11)

Ruta 40 starts at La Quiaca, a border town on the Jujuy altiplano at 3,442 m, directly across a bridge from Villazón in Bolivia. The milestone marking the northern end is the obligatory photograph, and almost everyone who takes it is about to drive south for several thousand kilometres.

La Quiaca

There is not much town: a grid of low buildings, a wind that never stops, and a market. Most travellers walk across to Villazón for an hour — the crossing is straightforward on foot with a passport — and come back with coca leaves and woven goods.

The Manca Fiesta, held each October, is the reason to time a visit. It is a pottery and barter fair that has been running for generations, and it fills the town.

Give yourself a day here before going higher. La Quiaca is already high enough that altitude will tell you whether you have acclimatised.

South across the Puna

From La Quiaca, Ruta 40 runs south through Abra Pampa and on across open Puna towards Susques. This is the emptiest driving in the Northwest: tussock grass, vicuñas, distant volcanoes, and villages an hour apart.

The road meets the Salinas Grandes where Ruta 40 crosses RN 52. The salt flat spans the Jujuy–Salta border and is worked commercially; local communities run guided walks out to the extraction pools, which is the right way to see it. Go in the morning, before the wind gets up.

Down to the Quebrada

From Salinas Grandes, RN 52 drops east over the Cuesta de Lipán — 4,170 m at the Abra de Potrerillos — and falls more than 1,500 m into Purmamarca, at the foot of the Cerro de los Siete Colores. From there the Quebrada de Humahuaca, a UNESCO World Heritage cultural landscape, runs north through Tilcara to Humahuaca itself.

This is the standard way to combine the two: Ruta 40 for the emptiness of the Puna, the Quebrada for the villages, the markets and the pre-Columbian sites.

Before you go up

The whole of this section sits above 3,400 m, and much of it above 4,000 m. Arrive from Salta or Jujuy over two days rather than one, drink more water than feels necessary, eat lightly and avoid alcohol the first night. If you are flying into Jujuy and driving straight to La Quiaca, build in a stop at Purmamarca or Tilcara on the way.

Fuel in La Quiaca and Abra Pampa. After that, Susques is the next dependable station.

Experiences

More tours for this trip

  • Promo Quebradas Cafayate and Humahuaca in 2 days
    Free cancellation
    Viator

    Culture · Gastronomy

    Promo Quebradas Cafayate and Humahuaca in 2 days

    I lived an unforgettable adventure in just 2 days! Discover the Cafayate Quebrada with its unique rock formations such as the Amphitheater and Devil’s Throat, and taste the best wines in your local wineries. The next…

    Full day · 48 h · Salta, Cafayate, Humahuaca

    From US$78

    5.0 out of 5 (11)

  • From Salta: Two full-day tours of Cafayate and Salinas Grandes
    Free cancellation
    Viator

    Culture

    From Salta: Two full-day tours of Cafayate and Salinas Grandes

    Two-day excursions through Salta and Jujuy. Tour to the wine-growing center of the province, touring the Quebrada de las Conchas and separating the Lerma Valley from the Calchaquí Valley. Wind erosion has formed a…

    Full day · 48 h · Salta, Cafayate, Salinas Grandes

    From US$68

    5.0 out of 5 (4)

  • Humahuaca Quebrada Full Day Tour
    Free cancellation
    Viator

    Culture

    Humahuaca Quebrada Full Day Tour

    We leave the province of Salta to enter the neighboring province of Jujuy, visiting the beautiful Quebrada de Humahuaca. Route 9 will begin the ascent, passing through the towns of Volcano (2,070 meters above sea…

    Full day · 11–12 h · Salta, Humahuaca

    From US$37

    5.0 out of 5 (6)